Mexican Casserole Recipe

The Best Mexican Casserole Recipe for Festive Family Dinners

Crafting a mouthwatering mexican casserole brings comfort and excitement to your dinner table.

Layers of vibrant ingredients promise a delightful culinary adventure.

Spices dance through each bite, creating a symphony of flavors.

Hearty and satisfying, this dish connects you with traditional mexican cuisine.

Home cooks appreciate how simple ingredients can produce such incredible results.

Melted cheese and bold seasonings make this recipe irresistible.

Storage Advice for Mexican Casserole

  • Store leftovers in an airtight container for up to 3-4 days in the refrigerator. Cool completely before sealing to prevent moisture buildup.
  • Wrap tightly in freezer-safe container or heavy-duty aluminum foil. Freeze for up to 2-3 months. Place a piece of plastic wrap directly on the surface to prevent freezer burn.
  • Place individual portions on microwave-safe plate. Heat in 30-second intervals, stirring between each interval until thoroughly warmed. Add a splash of water to prevent drying out.
  • Preheat oven to 350F. Cover casserole with foil to retain moisture. Warm for 15-20 minutes until heated through. Remove foil during last 5 minutes to restore crispy top layer.

FAQs About Mexican Casserole

  • Can I use ground turkey instead of beef?

Yes, ground turkey is an excellent lean protein alternative that works perfectly in this Mexican casserole. Just ensure you brown it thoroughly and drain any excess fat.

  • How spicy is this recipe?

The heat level depends on the Ro-tel tomatoes and taco seasoning you choose. For milder flavor, select mild versions of these ingredients. If you want more kick, opt for spicy Ro-tel or hot taco seasoning.

  • Is this dish freezer-friendly?

Absolutely! You can prepare the casserole, cover it tightly with plastic wrap and aluminum foil, and freeze for up to 3 months. Thaw overnight in the refrigerator before baking.

Why Mexican Casserole Is A Flavorful Crowd-Pleaser

  • Savor Hearty Flavors: Packed with robust ground beef, zesty Ro-tel tomatoes, and spicy taco seasoning, this Mexican casserole delivers a punch of southwestern taste that satisfies serious comfort food cravings.
  • Master Easy Layering: No complicated cooking techniques required – simply brown meat, mix ingredients, and create delicious layers of tortilla chips and cheese for a foolproof meal anyone can prepare.
  • Crowd-Pleasing Dinner: Perfect for family gatherings, potlucks, or weeknight meals, this dish appeals to both kids and adults with its crowd-pleasing combination of familiar Mexican-inspired ingredients that everyone loves.
  • Quick Weeknight Solution: With minimal prep work and straightforward assembly, this casserole transforms basic pantry staples into a delectable meal in under an hour, making it a go-to recipe for busy households.

Ingredients for Mexican Casserole

Protein Base:
  • Ground Beef: A hearty and flavorful meat that forms the main protein of the casserole.
  • Ranch Style Beans: Adds rich, seasoned bean texture and extra protein to the dish.
Dairy and Cheese:
  • Cheddar Cheese: Provides a sharp, melty topping that adds creamy richness to the casserole.
  • Sour Cream: A cool, tangy garnish that balances the warm, spicy flavors of the dish.
Flavor Enhancers:
  • Ro-tel Tomatoes, Onion: Bring bright, zesty freshness and additional depth to the meat mixture.
  • Taco Seasoning: Delivers classic Mexican-inspired spices and warmth to the overall flavor profile.
  • Cream of Chicken Soup: Creates a smooth, binding sauce that helps hold the casserole together.
Base and Crunch:
  • Tortilla Chips, Water: The chips provide a crispy base layer, while water helps create the right consistency for the meat mixture.
Garnish:
  • Salsa: A fresh, vibrant topping that adds extra tang and color to the finished casserole.

How to Prepare Mexican Casserole

Step 1: Heat Oven

Crank up your oven to a toasty 325F (165C) to get ready for a flavor explosion.

Step 2: Brown and Blend Meat Mixture

Grab a large skillet and cook ground beef until it’s beautifully browned. Drain away any extra fat. Then toss in these goodies:
  • Ranch Style beans
  • Ro-tel tomatoes
  • Chopped onion
  • Taco seasoning
  • Cream of chicken soup
  • Water

Let this delicious concoction simmer on medium-low heat until everything mingles and gets warm.

Step 3: Layer the Flavor Fest

Grab a 9×13-inch baking dish and give it a light grease. Now create mouthwatering layers:
  • Crushed tortilla chips as the first base
  • Half of the meat and bean mixture
  • Sprinkle of shredded cheddar cheese
  • Repeat those layers again for maximum deliciousness

Step 4: Bake to Perfection

Cover the dish with foil and slide it into the preheated oven. Bake for 20-30 minutes until everything is bubbling with excitement.

Step 5: Serve and Enjoy

Let the casserole rest for a few minutes. Top with a dollop of sour cream and a splash of salsa. Dive in and savor every bite of this Southwest comfort food!

Pro Tips for Perfect Mexican Casserole

  • Replace ground beef with ground turkey or plant-based crumbles for a leaner, healthier alternative.
  • Use low-sodium taco seasoning and reduced-fat cheese to cut down on calories and sodium intake.
  • Crush tortilla chips right before layering to maintain their crispiness and prevent sogginess.
  • Add diced bell peppers or jalapeños for extra flavor and nutrition boost.
  • Prepare the casserole ahead of time and refrigerate, then bake when ready to serve for a convenient meal prep option.

Delicious Variations for Mexican Casserole

  • Vegetarian Fiesta: Replace ground beef with black beans, quinoa, or roasted vegetables for a plant-based version packed with protein and flavor.
  • Spicy Southwest Kick: Add diced jalapeños, green chiles, and a sprinkle of cayenne pepper to amp up the heat and create a zesty experience.
  • Chicken Enchilada Style: Swap ground beef with shredded rotisserie chicken and incorporate enchilada sauce for a different protein-rich alternative.
  • Green Chile Fusion: Mix in diced green chiles, use pepper jack cheese, and top with fresh cilantro for a tangy southwestern spin on the classic recipe.

Pairing Ideas for Mexican Casserole

  • Pair with Zesty Margaritas: Blend fresh lime juice, tequila, and a touch of triple sec to cut through the rich, hearty flavors of the Mexican casserole.
  • Complement with Fresh Cilantro Slaw: Toss shredded cabbage with lime juice, chopped cilantro, and a pinch of salt to provide a crisp, tangy contrast to the warm, cheesy dish.
  • Enhance with Creamy Guacamole: Mash ripe avocados with diced onions, lime juice, and a sprinkle of salt to add a cool, smooth texture that balances the casserole's spicy notes.
  • Match with Mexican Rice: Prepare fluffy white rice with tomato sauce, garlic, and a dash of cumin to create a perfect side that soaks up the casserole's delicious sauce.
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Mexican Casserole Recipe

Mexican Casserole Recipe


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4.8 from 28 reviews

  • Total Time: 45 minutes
  • Yield: 6 1x

Description

Spicy Mexican casserole brings comfort and zest to dinner tables with layers of hearty ingredients and bold flavors. Home cooks can savor this delightful one-dish meal that combines rich textures and authentic southwestern seasonings, promising a satisfying culinary experience you’ll crave again.


Ingredients

Scale

Main Proteins:

  • 1 pound lean ground beef
  • 2 cups shredded cheddar cheese

Beans and Vegetables:

  • 1 can ranch style beans
  • 1 can ro-tel tomatoes
  • 1 small onion, chopped

Additional Ingredients:

  • 1 (10-12 ounces) bag tortilla chips, crushed
  • 1 package taco seasoning
  • 1 can cream of chicken soup
  • 1/2 cup water

Serving Suggestions:

  • Sour cream
  • Salsa

Instructions

  1. Warm the oven to 325F (165C), preparing a perfect environment for melding flavors.
  2. In a large skillet, transform ground beef into a rich, browned foundation, carefully draining excess grease.
  3. Introduce Ranch Style beans, Ro-tel tomatoes, diced onion, taco seasoning, cream of chicken soup, and water to the beef. Allow the mixture to simmer and harmonize over medium-low heat until thoroughly heated.
  4. Generously coat a 9×13-inch baking vessel with cooking spray to prevent sticking.
  5. Create a crisp base layer of crushed tortilla chips across the bottom of the dish.
  6. Lavish the first half of the robust meat and bean mixture over the chip foundation.
  7. Cascade a generous blanket of shredded cheddar cheese across the meat layer.
  8. Repeat the layering process: remaining chips, meat mixture, and a final crown of cheese.
  9. Shield the casserole with aluminum foil, then slide into the preheated oven for 20-30 minutes until the edges bubble and cheese melts completely.
  10. Once removed, allow the casserole to rest 5-10 minutes, letting flavors settle and intensify.
  11. Serve with a dollop of cool sour cream and vibrant salsa as the perfect finishing touches.

Notes

  • Swap ground beef with ground turkey or plant-based crumbles for a leaner, healthier alternative that cuts down on saturated fat.
  • Customize heat levels by choosing mild or spicy Ro-tel tomatoes and adjusting taco seasoning intensity to suit personal taste preferences.
  • Layer tortilla chips right before baking to maintain crispness and prevent soggy texture, ensuring a satisfying crunch in every bite.
  • Prepare casserole ahead of time by assembling and refrigerating, then bake when ready to serve, making it perfect for meal prep and busy weeknights.
  • Prep Time: 15 minutes
  • Cook Time: 30 minutes
  • Category: Lunch, Dinner
  • Method: Baking
  • Cuisine: Mexican

Nutrition

  • Serving Size: 6
  • Calories: 470 kcal
  • Sugar: 4 g
  • Sodium: 890 mg
  • Fat: 28 g
  • Saturated Fat: 14 g
  • Unsaturated Fat: 12 g
  • Trans Fat: 0.5 g
  • Carbohydrates: 28 g
  • Fiber: 5 g
  • Protein: 30 g
  • Cholesterol: 90 mg
Sarah Mitchell

Sarah Mitchell

Content Specialist & Home Cooking Enthusiast

Expertise

  • Making healthy, comforting meals that fit into real-life schedules
  • Planning balanced, single-serving meals for individuals and small families
  • Writing clear, practical food content with a focus on wellness and ease
  • Using seasonal ingredients to bring variety and freshness to everyday meals

Education

Asheville-Buncombe Technical Community College – Asheville, NC

  • Program: Diploma in Culinary Arts
  • Focus: Trained in the basics of professional cooking, with a strong focus on home-style meals, seasonal recipe development, and time-saving kitchen techniques for everyday use.

American Fitness Professionals & Associates – Online

  • Program: Nutrition and Wellness Consultant Certification
  • Focus: Studied how to make healthy eating simple, enjoyable, and accessible

Sarah’s passion for food was sparked by weekend trips to the farmers’ market and her belief that healthy meals should never feel boring.
After earning her culinary diploma and becoming a certified Nutrition and Wellness Consultant, she set out to help others fall in love with simple, wholesome cooking.
She’s all about celebrating the small wins in the kitchen: a colorful yogurt bowl, a new twist on a classic dish, or a homemade snack that feels just a little extra special.
Outside the kitchen, Sarah is a gardener at heart, a yoga enthusiast, and a believer that fresh herbs can brighten any meal, and any day.

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